Rino Rappuoli Selected Research

Antigens

1/2023	mRNA vaccines and hybrid immunity use different B cell germlines against Omicron BA.4 and BA.5.
1/2022	Self-amplifying mRNA-Based Vaccine Technology and Its Mode of Action.
1/2019	Safety of AS03-adjuvanted influenza vaccines: A review of the evidence.
1/2019	Genetic Meningococcal Antigen Typing System (gMATS): A genotyping tool that predicts 4CMenB strain coverage worldwide.
10/2018	Efficacy, immunogenicity, and safety of a parenteral vaccine against Helicobacter pylori in healthy volunteers challenged with a Cag-positive strain: a randomised, placebo-controlled phase 1/2 study.
5/2014	Combined adenovirus vector and hepatitis C virus envelope protein prime-boost regimen elicits T cell and neutralizing antibody immune responses.
8/2013	Human circulating influenza-CD4+ ICOS1+IL-21+ T cells expand after vaccination, exert helper function, and predict antibody responses.
8/2013	Correlates of protection against influenza infection in humans--on the path to a universal vaccine?
6/2012	One dose of an MF59-adjuvanted pandemic A/H1N1 vaccine recruits pre-existing immune memory and induces the rapid rise of neutralizing antibodies.
3/2012	Vaccines for the future: learning from human immunology.

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Rino Rappuoli Research Topics

Disease

67	Infections 02/2024 - 01/2002
36	Communicable Diseases (Infectious Diseases) 11/2023 - 05/2003
30	Human Influenza (Influenza) 01/2019 - 12/2005
23	COVID-19 05/2024 - 01/2020
16	Meningococcal Infections 11/2022 - 06/2002
10	Neoplasms (Cancer) 02/2024 - 05/2011
10	Tuberculosis (Tuberculoses) 01/2022 - 11/2006
10	Diphtheria 08/2014 - 02/2003
7	Virus Diseases (Viral Diseases) 05/2024 - 06/2012
7	Malaria 01/2022 - 05/2011
6	Bacterial Infections (Bacterial Infection) 01/2021 - 01/2002
6	Whooping Cough (Pertussis) 11/2009 - 07/2003
5	Acquired Immunodeficiency Syndrome (AIDS) 01/2022 - 11/2005
4	Emerging Communicable Diseases (Emerging Infectious Diseases) 01/2022 - 10/2009
4	Meningitis 10/2020 - 06/2002
3	Bacillary Dysentery (Shigellosis) 09/2023 - 09/2021
3	Autoimmune Diseases (Autoimmune Disease) 01/2022 - 07/2011
3	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2022 - 08/2014
3	Tetanus 07/2011 - 01/2004
2	Severe Acute Respiratory Syndrome 01/2023 - 11/2005
2	Typhoid Fever (Typhoid) 11/2022 - 01/2020
2	Neglected Diseases 11/2022 - 09/2009
2	Parasitic Diseases (Parasitic Disease) 01/2022 - 01/2016
2	Persistent Infection 01/2021 - 05/2014
2	Narcolepsy 01/2019 - 07/2015
2	Pneumococcal Infections 11/2014 - 07/2011
2	Noncommunicable Diseases 08/2014 - 10/2011
2	Smallpox (Variola) 06/2014 - 05/2010
2	Meningococcal Meningitis 11/2013 - 02/2012
2	Sepsis (Septicemia) 01/2012 - 06/2002
2	Urinary Tract Infections (Urinary Tract Infection) 01/2012 - 03/2010
2	Vaccine-Preventable Diseases 07/2011 - 12/2008
1	Hepatitis B 02/2024
1	Prostatic Neoplasms (Prostate Cancer) 02/2024
1	Breakthrough Infections 10/2023
1	Necrosis 01/2021
1	Pharyngitis (Sore Throat) 11/2020

Drug/Important Bio-Agent (IBA)

128	VaccinesIBA 02/2024 - 01/2002
25	AntigensIBA 01/2023 - 06/2002
21	Proteins (Proteins, Gene)FDA Link 01/2022 - 01/2002
17	AntibodiesIBA 01/2023 - 06/2002
12	Influenza Vaccines (Influenza Vaccine)FDA Link 01/2019 - 04/2006
11	Monoclonal AntibodiesIBA 05/2024 - 08/2004
11	Neutralizing AntibodiesIBA 01/2022 - 02/2003
10	Anti-Bacterial Agents (Antibiotics)IBA 01/2021 - 06/2002
7	GlycoconjugatesIBA 11/2023 - 09/2004
7	CRM197 (non-toxic variant of diphtheria toxin)IBA 11/2022 - 02/2004
7	Conjugate VaccinesIBA 11/2022 - 12/2005
6	Messenger RNA (mRNA)IBA 10/2023 - 11/2015
5	mRNA VaccinesIBA 10/2023 - 12/2021
4	Polysaccharides (Glycans)IBA 11/2023 - 04/2008
4	EpitopesIBA 01/2023 - 03/2010
4	Cytotoxins (Cytolysins)IBA 10/2018 - 09/2008
4	Membrane Proteins (Integral Membrane Proteins)IBA 05/2017 - 02/2006
4	CytokinesIBA 11/2015 - 04/2004
4	MF59 oil emulsionIBA 01/2015 - 08/2009
4	Carrier Proteins (Binding Protein)IBA 07/2011 - 04/2008
4	IronIBA 03/2010 - 10/2003
3	Antiviral Agents (Antivirals)IBA 05/2024 - 01/2008
3	N-(2-cyanoethylene)urea (BA 1)IBA 11/2022 - 01/2022
3	Immunoglobulin G (IgG)IBA 09/2021 - 02/2010
3	aluminum sulfate (alum)IBA 02/2021 - 01/2016
3	E coli heat-labile enterotoxinIBA 01/2017 - 09/2009
3	Viral ProteinsIBA 07/2015 - 08/2004
3	Inactivated VaccinesIBA 01/2015 - 04/2006
3	Synthetic Vaccines (Recombinant Vaccines)IBA 01/2014 - 05/2013
3	Subunit VaccinesIBA 08/2013 - 09/2009
2	glyceryl methyl methacrylateIBA 09/2023 - 10/2018
2	N-methyl-valyl-amiclenomycin (BA 2)IBA 11/2022 - 01/2022
2	COVID-19 VaccinesIBA 01/2022 - 10/2020
2	pandemrixIBA 01/2019 - 07/2015
2	SolutionsIBA 01/2018 - 01/2004
2	Peptides (Polypeptides)IBA 07/2015 - 08/2009
2	Pertussis ToxinIBA 11/2014 - 01/2005
2	Diphtheria Toxoid (Vaccine, Diphtheria)FDA Link 11/2014 - 03/2010
2	Hemagglutinins (Hemagglutinin)IBA 08/2013 - 06/2011
2	Broadly Neutralizing AntibodiesIBA 08/2013 - 06/2011
2	Complement Factor H (Factor H)IBA 07/2011 - 05/2011
2	ToxoidsIBA 07/2011 - 01/2005
2	Glycoproteins (Glycoprotein)IBA 06/2011 - 11/2005
2	Bacterial Proteins (Bacterial Protein)IBA 05/2011 - 12/2002
2	Pertussis VaccineIBA 05/2011 - 01/2005
2	EnzymesIBA 05/2011 - 11/2009
2	Complement System Proteins (Complement)IBA 07/2010 - 12/2003
2	beta-GlucansIBA 03/2010 - 02/2010
2	Meningococcal Vaccines (Meningococcal Vaccine)IBA 03/2010 - 10/2004
2	Immunoglobulin A (IgA)IBA 12/2005 - 12/2004
2	ChitosanIBA 12/2005 - 02/2004
1	BNT162 VaccineIBA 10/2023
1	vitamin B 12 factor III (HMQC)IBA 09/2022
1	MAD0004J08IBA 01/2022
1	Mannose-Binding Lectin (Mannan-Binding Lectin)IBA 01/2022
1	Biomarkers (Surrogate Marker)IBA 01/2022
1	Viral AntigensIBA 12/2021
1	4CMenB vaccineIBA 12/2021
1	SARS-CoV-2 spike proteinIBA 01/2021
1	Immunoglobulins (Immunoglobulin)IBA 01/2021
1	Staphylococcal Protein A (Protein A)IBA 01/2021

Therapy/Procedure

10	Therapeutics 01/2023 - 06/2002
1	Immunotherapy 02/2024